Differences in Alcohol Consumption Duration on Cholesterol Levels
Keywords:
duration of alcohol consumption, acetaldehyde, cholesterol level, POCT, high-riskAbstract
Background: Alcohol is toxic containing hydrophilic ethanol so that it easily enters the body which will be converted into acetaldehyde by aldehyde dehydrogenase (ALDH) and oxidized to acetate. Excessive acetate is converted into acetyl-CoA which is converted into fatty acids that will continue to accumulate to increase cholesterol. Consuming alcohol within 5 years with a frequency of 3-4x per week can increase cholesterol levels. The study aimed to determine the difference in the duration of alcohol consumption (≤ 5 and > 5 years) on cholesterol levels. Method: Analytic observational research with a cross-sectional approach. Samples were taken randomly from as many as 20 people who consumed alcohol ≤ 5 and > 5 years at a cafe in Salatiga. Cholesterol levels were examined using the POCT method, and then cholesterol levels were statistically analyzed using Shapiro Wil and Independent T-Test. Result: The mean cholesterol levels of respondents who consumed alcohol ≤ 5 and > 5 years were 172.30 ± 16.63 mg/dL and 236.80 ± 34.74 mg/dL, respectively. Cholesterol levels of respondents who consume alcohol ≤ 5 are still in the normal category while cholesterol levels of respondents who consume > 5 years fall into the high-risk category. Based on the statistical results, it is known that the data is normally distributed and there are differences between respondents who consume alcohol ≤ 5 years and > 5 years. Conclusion: The cholesterol levels of respondents who consumed alcohol > 5 years were higher than those who consumed alcohol ≤ 5 years.
References
. WHO, “Alkohol,” 2024. [Online]. Available: https://www.who.int/news-room/fact-sheets/detail/alcohol
. I. Darmawati, L. Nurlita, and H. Ropi, “Pengetahuan Remaja Tentang Konsumsi Alkohol,” J. Terpadu Ilmu Kesehat., vol. 9, no. 2, pp. 139–140, 2020.
. A. Ahdiat, “10 Provinsi dengan Peminum Alkohol Terbanyak,” 2024. https://databoks.katadata.co.id/datapublish/2024/07/19/10-provinsi-dengan-peminum-alkohol-terbanyak
. F. D. Rodriguez and R. Coveñas, “Biochemical mechanisms associating alcohol use disorders with cancers,” Cancers (Basel)., vol. 13, no. 14, pp. 0–39, 2021, doi: 10.3390/cancers13143548.
. K. D. Aprellia, M. A. Purwanto, N. K. Putri, D. S. Aghata, and L. D. Dewi A, “Dampak Mengkonsumsi Minuman Keras Pada Kalangan Remaja,” J. Kaji. dan Penelit. Umum, vol. 2, no. 3, pp. 36–49, 2024, doi: https://doi.org/10.47861/jkpu-nalanda.v1i3.1008.
. A. N. Batara, E. Pangkahila, and H. Polii, “Hubungan Konsumsi Alkohol dengan Kadar High Density Lipoprotein,” J. e-Biomedik, vol. 6, no. 2, pp. 2–5, 2018, doi: 10.35790/ebm.6.2.2018.22155.
. W. Hanifah, W. S. Oktavia, and H. Nisa, “Faktor Gaya Hidup Dan Penyakit Jantung Koroner: Review Sistematik Pada Orang Dewasa Di Indonesia,” Penelit. Gizi dan Makanan (The J. Nutr. Food Res., vol. 44, no. 1, pp. 45–58, 2021, doi: 10.22435/pgm.v44i1.4187.
. I. P. A. D. Hita, M. A. Juliansyah, D. Pranata, K. Ayu, I. K. A. P. Indrawan, and N. G. A. L. Rusmayani, “Hubungan kadar kolesterol dan tekanan darah dengan status gizi lansia member senam di masa pandemi covid-19,” Multilater. J. Pendidik. Jasm. dan Olahraga, vol. 21, no. 1, pp. 31–42, 2022, doi: 10.20527/multilateral.v21i1.11326.
. M. Nurman and A. Afifah, “Studi Perbandingan Jus Apel Dan Jus Alpukat Terhadap Penurunan Kadar Kolesterol Pada Orang Yang Mengalam Hiperkolesterolemia Di Wilayah Kerja Puskesmas Bangkinang Kota,” J. Ners, vol. 3, no. 2, pp. 112–120, 2019, doi: 10.31004/jn.v3i2.840.
. T. Susanto, H. Rasny, L. A. Susumaningrum, R. A. Yunanto, and K. R. M. Nur, “Prevalence of hypertension and predictive factors of self-efficacy among elderly people with hypertension in institutional-based rehabilitation in Indonesia,” Kontakt, vol. 21, no. 1, pp. 14–21, 2019, doi: 10.32725/kont.2018.007.
. N. Kurniati, W. S. Zaini, and A. M. Rohmah, “Perbandingan Kadar Kolestrol Darah Kapiler Metode POCT dengan Serum Metode Enzimatik CHOD-PAP pada Mahasiswa TLM Poltekkes Banten,” J. Med. Lab. Res., vol. 1, no. 2, pp. 45–49, 2023, doi: 10.36743/jomlr.v1i2.471.
. Stefhanie Affrianti and Adelia Febriyossa, “Perbedaan Kadar Kolesterol Total Darah Pada Serum Yang Disentrifus Dan Tidak Disentrifus Di Klinik Ratnasari Medical Centre,” J. Med. Lab., vol. 1, no. 1, pp. 6–9, 2022, doi: 10.57213/medlab.v1i1.2.
. K. J. Biddinger et al., “Association of Habitual Alcohol Intake with Risk of Cardiovascular Disease,” JAMA Netw. Open, vol. 5, no. 3, p. E223849, 2022, doi: 10.1001/jamanetworkopen.2022.3849.
. L. N. Hanifah, “Literature Review: Factors Affecting Alcohol Consumption and the Impact of Alcohol on Health Based on Behavioral Theory,” Media Gizi Kesmas, vol. 12, no. 1, pp. 453–462, 2023, doi: 10.20473/mgk.v12i1.2023.453-462.
. M. W. Manoppo, F. F. Pitoy, and K. B. Tampi, “Hubungan Tingkat Stres dengan Konsumsi Alkohol pada Remaja,” MAHESA Malahayati Heal. Student J., vol. 3, no. 6, pp. 1710–1725, 2023, doi: 10.33024/mahesa.v3i6.10585.
. S. Jeon and R. Carr, “Alcohol effects on hepatic lipid metabolism,” J. Lipid Res., vol. 61, no. 4, pp. 470–479, 2020, doi: 10.1194/jlr.R119000547.
. H. Y. So, P. P. Chen, G. K. C. Wong, and T. T. N. Chan, “Simulation in medical education,” J. R. Coll. Physicians Edinb., vol. 49, no. 1, pp. 52–57, 2019, doi: 10.4997/JRCPE.2019.112.
. C. Bode, “Alcohol’s role in gastrointestinal tract disorders,” Alcohol Res. Heal., vol. 21, no. 1, pp. 76–83, 1997.
. K. R. Feingold, Introduction to Lipids and Lipoproteins. MDText.com, Inc, 2024. [Online]. Available: https://www.ncbi.nlm.nih.gov/books/NBK305896/
. S. C. Larsson, S. Burgess, A. M. Mason, and K. Michaëlsson, “Alcohol Consumption and Cardiovascular Disease: A Mendelian Randomization Study,” Circ. Genomic Precis. Med., vol. 13, no. 3, p. E002814, 2020, doi: 10.1161/CIRCGEN.119.002814.
. S. E. Brennan et al., “Long-term effects of alcohol consumption on cognitive function: A systematic review and dose-response analysis of evidence published between 2007 and 2018,” Syst. Rev., vol. 9, no. 1, pp. 1–39, 2020, doi: 10.1186/s13643-019-1220-4.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Prosiding Seminar Kesehatan Masyarakat
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.